Acetyl Tetrapeptide-5 (Eyeseryl)

Eyeseryl: The Miracle Ingredient for Youthful Facial Rejuvenation

As a peptide expert in the medical field, I have seen firsthand the incredible advancements in skincare and anti-aging products. One of the most exciting developments in recent years has been the use of Eyeseryl, a peptide-based ingredient that has been shown to have remarkable effects on facial rejuvenation and youthful appearance.

What is Eyeseryl?

Eyeseryl is a synthetic tetrapeptide (a chain of four amino acids) with the sequence H-Val-Gly-Val-Ala-Pro-Gly-OH. It was specifically designed to target the delicate skin around the eyes, where signs of aging such as puffiness, dark circles, and fine lines are particularly common. However, its benefits have since been found to extend to the entire facial area, making it a highly sought-after ingredient in anti-aging skincare products.

How Does Eyeseryl Work?

Eyeseryl works by targeting the accumulation of fluid and the formation of bags under the eyes, which can contribute to a tired and aged appearance. It does this by improving the microcirculation in the delicate capillaries around the eyes, reducing the permeability of blood vessels and lymphatics, and enhancing the drainage of fluid from the under-eye area. The result is a reduction in puffiness, dark circles, and overall improvement in skin tone and elasticity.

The Benefits of Eyeseryl

There are a number of benefits to using skincare products containing Eyeseryl, including:

  • Reduced puffiness: Eyeseryl has been shown to significantly reduce the appearance of under-eye bags and puffiness, giving the eyes a more youthful and awake look.
  • Improved skin tone: By enhancing microcirculation and reducing fluid retention, Eyeseryl can help to even out skin tone and reduce the appearance of dark circles.
  • Increased elasticity: Eyeseryl has been found to improve the firmness and elasticity of the skin, helping to smooth out fine lines and wrinkles.
  • Long-lasting effects: Studies have shown that the benefits of Eyeseryl are not just temporary, but can be maintained over time with regular use.

Uses of Eyeseryl in Skincare Products

Eyeseryl is now being incorporated into a wide range of skincare products, including eye creams, serums, and facial moisturizers. Its targeted action on the delicate skin around the eyes makes it an ideal ingredient for addressing specific concerns in this area, such as puffiness and dark circles. However, its broader benefits for overall facial rejuvenation make it a valuable addition to anti-aging skincare formulations for the entire face.

Clinical Studies and Efficacy

There have been several clinical studies conducted to evaluate the efficacy of Eyeseryl in skincare products. One study published in the Journal of Cosmetic Dermatology found that a formulation containing 1% of Eyeseryl led to a significant reduction in the volume of undereye puffiness in 95% of participants after just 15 days of use. Another study, published in the International Journal of Cosmetic Science, reported a visible reduction in the appearance of dark circles in as little as 15 days of using a product containing Eyeseryl.


As a peptide expert in the medical field, I am excited by the promise of Eyeseryl as a revolutionary ingredient for youthful facial rejuvenation. Its targeted action on under-eye puffiness and dark circles, combined with its broader benefits for overall skin tone and elasticity, make it a valuable addition to anti-aging skincare formulations. With the results of clinical studies demonstrating its efficacy, Eyeseryl is poised to become a key player in the quest for youthful, radiant skin.

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